腹腔高温化疗(HIPEC)

什么是高温腹腔化疗(HIPEC)?

Hyperthermic intraperitoneal chemotherapy (HIPEC) is a specialized treatment for cancerous tumors that start in or have spread to the abdomen. 治疗期间, 外科医生切除肿瘤, then places a dose of heated chemotherapy drug directly into your abdomen. This heated chemotherapy drug can kill cancer cells and lower the risk of the tumors returning.

为什么选择UCLA健康中心进行HIPEC治疗?

UCLA Health was one of the first centers in Southern California to begin offering HIPEC surgery, in 2015. Early adoption of this procedure makes us one of the most experienced teams in our region providing HIPEC treatment. You can trust us to provide innovative, effective cancer treatment.

我们课程的亮点包括:

建立专业知识: Our surgical 肿瘤学家s have years of experience in HIPEC treatment. HIPEC疗法并不适合所有人. Our team has the expertise to determine if you’re a good candidate for the treatment, 增加其有效性的机会.    

协调护理: 我们会密切配合你的建议 肿瘤学家 在整个治疗过程中找到正确的护理计划. Clinic coordinators help schedule appointments quickly and smoothly.  

前沿的治疗: 作为一个主要学术中心的教员, UCLA Health physicians are active researchers who study the most promising new treatments. We continually offer you leading-edge cancer therapies, often before they’re widely available.

我们治疗的癌症类型

Our surgical 肿瘤学家s use HIPEC to treat tumors that have spread within your abdomen but aren’t expected to spread to other organs. We utilize HIPEC to treat only low-grade tumors (ones that grow and spread slowly).

HIPEC可以治疗以下疾病:

阑尾癌伴癌变: Cancer that starts in the small pouch on the right side of your low belly (appendix) and spreads to the rest of the abdomen

结肠癌或直肠癌合并癌变: Cancer that starts in the longest part of your large intestine (colon) or the end of your large intestine (rectum) and spreads to your abdomen

阑尾粘液性肿瘤: A tumor in your appendix that starts forming in mucin, the main component of mucus  

卵巢癌伴癌变: Cancer that starts in the female glands that produce eggs (ovaries) and spreads to the abdomen

腹膜间皮瘤: 始于腹膜的癌症, 膜包裹腹部和其他器官的膜, 比如肝和肺

原发性腹膜癌: 始于腹膜的癌症, a thin tissue that covers the entire abdominal cavity and its organs

HIPEC手术期间会发生什么

治疗前, your surgical 肿瘤学家 performs a comprehensive evaluation to determine if HIPEC is right for you. 他们会记录完整的病史, 检查你的图像和实验室测试, 如果需要，还可以要求进行新的测试. They work closely with your referring 肿瘤学家 to choose the treatment they believe will be most effective for you.

Each HIPEC procedure varies slightly, depending on the size and location of the tumor. 一般来说，你的外科医生:

1. Removes the entire tumor and any diseased tissue or abdominal organs affected by the tumor. They may operate through one long incision (open approach) or through tiny incisions using special tools and a camera (laparoscopic approach)  
2. Places small, hollow tubes (catheters) containing chemotherapy drugs into your abdomen
3. Connects the catheters to a perfusion machine that heats the medications
4. Allows the heated chemotherapy drugs to circulate in your abdomen for one to two hours
5. Removes the catheters and rinses your abdomen with a salt solution
6. 缝合切口

HIPEC的好处

HIPEC provides another effective treatment option that offers good long-term outcomes for people with advanced cancer. The combination of heat and chemotherapy used in HIPEC kills cancer cells and prevents tumor regrowth.

During HIPEC, chemotherapy medications don’t cross into your bloodstream. This allows us to use a higher dose of medication than we can with intravenous (IV) chemotherapy, 副作用的风险更低.

HIPEC恢复及随访

The overall surgery and recovery time depends on how much a tumor has spread and the extent of surgery. You’ll typically stay in the hospital for six to 12 days after HIPEC surgery. 完全康复可能需要4到8周.

You’ll follow up with your surgeon about two weeks after leaving the hospital. HIPEC手术对很多人都有效, and you may not need intravenous (IV) chemotherapy after treatment. 然而, you’ll likely need ongoing follow-up with your medical 肿瘤学家 to monitor whether or not the tumor returns.

认识我们的团队

Our surgical 肿瘤学家s are among the most established HIPEC experts in the region. We provide personalized, effective treatment plans to meet your needs.

皇冠hga025

呼叫 310-319-4080 to request an appointment with a surgical 肿瘤学家 at UCLA Health.